Publications

*= contributed equally ^= corresponding author

Sheu-Gruttadauria J^, Yan X, Stuurman N, Ogrean RO, Lin S, Floor SN, Vale RD. “Nucleolar dynamics are determined by the ordered assembly of the ribosome.” J Cell Biol 2 November 2026; 225 (11): e202605096.

Liboy-Lugo JM, Espinoza CA, Sheu-Gruttadauria J, Park JE, Xu A, Jowhar Z, Gao AL, Carmona-Negrón JA, Wittmann T, Jura N, Floor, SN^. “G3BP isoforms differentially affect stress granule assembly and gene expression during cellular stress.” Mol Biol Cell. 2024 Nov 1;35(11):ar140. : 2024.02.06.579149.

Pawlica P, Sheu-Gruttadauria J, MacRae IJ, Steitz JA^. “How Complementary Targets Expose the microRNA 3' End for Tailing and Trimming during Target-Directed microRNA Degradation.” Cold Spring Harb Symp Quant Biol. 2020 Feb 04.

Sheu-Gruttadauria J*, Pawlica P*, Klum SM, Wang S, Yario TA, Schirle Oakdale NT, Steitz JA^, MacRae IJ^. “Structural Basis for Target-Directed MicroRNA Degradation.” Mol Cell. 2019 09 19; 75(6):1243-1255.e7.

Sheu-Gruttadauria J*, Xiao Y*, Gebert LF, MacRae IJ^. “Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.” EMBO J. 2019 07 01; 38(13):e101153.

Ziv O, Gabryelska MM, Lun ATL, Gebert LFR, Sheu-Gruttadauria J, Meredith LW, Liu ZY, Kwok CK, Qin CF, MacRae IJ, Goodfellow I, Marioni JC, Kudla G, Miska EA^. “COMRADES determines in vivo RNA structures and interactions.” Nat Methods. 2018 10; 15(10):785-788.

Sheu-Gruttadauria J, MacRae IJ^. “Phase Transitions in the Assembly and Function of Human miRISC.” Cell. 2018 05 03; 173(4):946-957.e16.

Sheu-Gruttadauria J, MacRae IJ^. “Structural Foundations of RNA Silencing by Argonaute.” J Mol Biol. 2017 08 18; 429(17):2619-2639.

Suter SR*, Sheu-Gruttadauria J*, Schirle NT, Valenzuela R, Ball-Jones AA, Onizuka K, MacRae IJ^, Beal PA^. “Structure-Guided Control of siRNA Off-Target Effects.” J Am Chem Soc. 2016 07 20; 138(28):8667-9.

Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo C†, MacRae IJ^. “Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.” Elife. 2015 Sep 11; 4.

Schirle NT, Sheu-Gruttadauria J, MacRae IJ^. “Structural basis for microRNA targeting.” Science. 2014 Oct 31; 346(6209):608-13.

Kang H, Louie J, Weisman A, Sheu-Gruttadauria J, Davis-Dusenbery BN, Lagna G, Hata A^.“Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway.” J Biol Chem. 2012 Nov 09; 287(46):38656-64.